Description

Ethyl 3,5-Difluoro-4-Nitrobenzoate is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research institutions and industrial manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of fluorinated drug candidates, including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and stability.
• Material Science: Serves as a precursor for liquid crystals, organic semiconductors, and other advanced functional materials.
• Organic Synthesis: Employed in cross-coupling reactions, esterifications, and nucleophilic aromatic substitution to introduce the difluoro-nitrobenzoate moiety.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and fluorination chemistry.

Basic Information

Product Name	Ethyl 3,5-Difluoro-4-Nitrobenzoate
CAS No.	1803870-78-1
Molecular Formula	C9H7F2NO4
Molecular Weight	231.16 g/mol
Synonyms	Benzoic acid, 3,5-difluoro-4-nitro-, ethyl ester; Ethyl 3,5-difluoro-4-nitrobenzoate; 4-Nitro-3,5-difluorobenzoic acid ethyl ester; 3,5-Difluoro-4-nitrobenzoic acid ethyl ester; Ethyl 4-nitro-3,5-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 3,5-Difluoro-4-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.