Description

Methyl 4-Bromo-3,5-Difluorobenzoate CAS NO 1803565-64-1 is a high-purity fluorinated and brominated aromatic ester, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to introduce halogenated aromatic units into specialty polymers, enhancing flame retardancy and chemical resistance.
• Organic Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	Methyl 4-Bromo-3,5-Difluorobenzoate
CAS No.	1803565-64-1
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	4-Bromo-3,5-difluorobenzoic Acid Methyl Ester; Methyl 4-Bromo-3,5-difluorobenzoate; Benzoic acid, 4-bromo-3,5-difluoro-, methyl ester; 3,5-Difluoro-4-bromobenzoic Acid Methyl Ester; Methyl 3,5-Difluoro-4-bromobenzoate; 4-Bromo-3,5-difluorobenzoic acid, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-3,5-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.