Description

Methyl3-Bromo-2-Chloro-6-Fluorobenzoate CAS NO 1784053-31-1 is a high-purity, multi-halogenated benzoate ester serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized aromatic scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where precise halogen substitution patterns are required for bioactivity and molecular tuning.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize labeled compounds or molecular probes for studying biological mechanisms and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Methyl3-Bromo-2-Chloro-6-Fluorobenzoate
CAS No.	1784053-31-1
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	Methyl 3-Bromo-2-chloro-6-fluorobenzoate; 3-Bromo-2-chloro-6-fluorobenzoic Acid Methyl Ester; Benzoic acid, 3-bromo-2-chloro-6-fluoro-, methyl ester; Methyl 3-bromo-2-chloro-6-fluorobenzoate; Methyl ester of 3-bromo-2-chloro-6-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our production of Methyl3-Bromo-2-Chloro-6-Fluorobenzoate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our facilities are capable of supporting development under cGMP and ISO 9001 guidelines for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. Contents may be moisture-sensitive.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.