Description

Benzoic Acid, 3-(Difluoromethyl)-4-Fluoro- is a high-purity, fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring both difluoromethyl and fluorine groups, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic materials, contributing to desired dielectric and optical properties.
• Organic Synthesis & Catalysis: Employed as a versatile intermediate in cross-coupling reactions and other catalytic processes to introduce fluorinated aromatic motifs.
• Chemical Research: Utilized in academic and industrial R&D for exploring structure-activity relationships (SAR) and developing new fluorination methodologies.

Basic Information

Product Name	Benzoic Acid, 3-(Difluoromethyl)-4-Fluoro-
CAS No.	1781570-25-9
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	4-Fluoro-3-(difluoromethyl)benzoic acid; 3-(Difluoromethyl)-4-fluorobenzoic acid; 4-Fluoro-α,α-difluoro-m-toluic acid; 2-Fluoro-5-(difluoromethyl)benzoic acid; 5-(Difluoromethyl)-2-fluorobenzoic acid; BA-3DF-4F (abbrev.); 1781570-25-9; Benzoic acid, 4-fluoro-3-(difluoromethyl)-
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-(Difluoromethyl)-4-Fluoro- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.