Description

3,4-Dichloro-5-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative. This compound is a critical synthetic intermediate prized for its unique combination of halogen and trifluoromethoxy substituents, which impart significant electronic and steric properties. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and biological activity.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Chemical Biology Probes: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific halogenated benzoic acid derivative.

Basic Information

Product Name	3,4-Dichloro-5-(Trifluoromethoxy)Benzoic Acid
CAS No.	1706458-45-8
Molecular Formula	C8H3Cl2F3O3
Molecular Weight	275.01 g/mol
Synonyms	3,4-Dichloro-5-(trifluoromethoxy)benzoic acid; Benzoic acid, 3,4-dichloro-5-(trifluoromethoxy)-; 5-(Trifluoromethoxy)-3,4-dichlorobenzoic acid; 3,4-Dichloro-α,α,α-trifluoroanisic acid (related); 3,4-Dichloro-5-(trifluoromethoxy)benzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.