Description

3,4-Dichloro-5-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid building block. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystal compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring lipophilicity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Specialty Polymer Modifier: Can be incorporated into polymer chains to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide couplings to construct complex molecular architectures in R&D settings.

Basic Information

Product Name	3,4-Dichloro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	1706458-41-4
Molecular Formula	C8H3Cl2F3O2
Molecular Weight	259.01 g/mol
Synonyms	3,4-Dichloro-α,α,α-trifluoro-m-toluic acid; 5-(Trifluoromethyl)-3,4-dichlorobenzoic acid; Benzoic acid, 3,4-dichloro-5-(trifluoromethyl)-; 3,4-Dichloro-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 3,4-Dichloro-5-(Trifluoromethyl)Benzoic Acid is monitored through in-process controls and final release testing to ensure batch-to-batch consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system supports compliance with cGMP and ISO standards as required for advanced intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.