Description

4-Fluoro-3-Methyl-2-(Trifluoromethyl)Benzoic Acid is a high-value, multi-fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the aromatic ring, makes it indispensable for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups improve compound activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing components in electronic display materials, enhancing their dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with improved chemical resistance, weatherability, and surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and for introducing fluorinated aromatic motifs into complex molecular architectures in medicinal chemistry research.
• Material Science Research: Used in the development of novel fluorinated organic compounds for applications in coatings, adhesives, and advanced functional materials.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-Methyl-2-(Trifluoromethyl)Benzoic Acid
CAS No.	1706436-25-0
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	2-(Trifluoromethyl)-4-fluoro-3-methylbenzoic acid; 4-Fluoro-3-methyl-α,α,α-trifluoro-o-toluic acid; 3-Methyl-4-fluoro-2-(trifluoromethyl)benzoic acid; Benzoic acid, 4-fluoro-3-methyl-2-(trifluoromethyl)-; 4-Fluoro-3-methyl-2-trifluoromethylbenzoic acid; 2-Trifluoromethyl-4-fluoro-3-methylbenzoic acid; 1706436-25-0
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methyl-2-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.