Description

2-(2,2-Difluoro-2H-1,3-Benzodioxol-5-Yl)-2,2-Difluoroacetic Acid is a high-value, multi-fluorinated organic acid building block, distinguished by its unique benzodioxole core. This compound is critical for introducing difluoroacetic acid moieties into complex molecular architectures, enabling the fine-tuning of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, where the fluorine atoms can improve pesticidal activity and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials that require fluorinated aromatic components for specific thermal or chemical resistance properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, fluorinated heterocycles and other sophisticated organic molecules.
• Ligand and Catalyst Development: The carboxylic acid group and unique fluorinated structure make it a candidate for developing novel ligands in catalytic systems.

Basic Information

Product Name	2-(2,2-Difluoro-2H-1,3-Benzodioxol-5-Yl)-2,2-Difluoroacetic Acid
CAS No.	1638764-98-3
Molecular Formula	C9H4F4O4
Molecular Weight	252.12 g/mol
Synonyms	2,2-Difluoro-2-(2,2-difluoro-1,3-benzodioxol-5-yl)acetic acid; 5-(Carboxydifluoromethyl)-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-2-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)acetic Acid; 2-(2,2-Difluoro-1,3-benzodioxol-5-yl)-2,2-difluoroacetic acid; 2,2-Difluoro-2-(2,2-difluoro-1,3-benzodioxol-5-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(2,2-Difluoro-2H-1,3-Benzodioxol-5-Yl)-2,2-Difluoroacetic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate chemical hygiene practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.