Description

5-Bromo-2-Fluoro-4-Iodo-Benzoic Acid Methyl Ester is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on new active ingredients, especially in the fields of medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Iodo-Benzoic Acid Methyl Ester
CAS No.	1626409-45-7
Molecular Formula	C8H5BrFIO2
Molecular Weight	358.93 g/mol
Synonyms	Methyl 5-Bromo-2-Fluoro-4-Iodobenzoate; Benzoic acid, 5-bromo-2-fluoro-4-iodo-, methyl ester; 5-Bromo-2-fluoro-4-iodobenzoic acid methyl ester; Methyl 5-bromo-2-fluoro-4-iodobenzoate; 1626409-45-7; 5-Br-2-F-4-I-Benzoic Acid Me Ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Iodo-Benzoic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of our global customer base in the fine chemical and pharmaceutical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat and incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.