Description

trans-2-(3-Fluoro-4-Methoxyphenyl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically versatile cyclopropane derivative featuring a fluorinated aromatic moiety. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the construction of complex molecules with targeted biological activity. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a structurally constrained, fluorinated pharmacophore into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas like CNS disorders and oncology.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Material Science Precursor: Serves as a monomer or functionalizing agent for advanced polymers and liquid crystals.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and biochemical probe design.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	trans-2-(3-Fluoro-4-Methoxyphenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	1609290-12-1
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	(1R,2S)-2-(3-Fluoro-4-methoxyphenyl)cyclopropane-1-carboxylic acid; (1S,2R)-2-(3-Fluoro-4-methoxyphenyl)cyclopropane-1-carboxylic acid; trans-2-(3-Fluoro-4-methoxyphenyl)cyclopropanecarboxylic acid; 2-(3-Fluoro-4-methoxyphenyl)cyclopropanecarboxylic acid; 3-Fluoro-4-methoxy-trans-cyclopropanecarboxylic acid; Fluoromethoxy Cyclopropane Carboxylic Acid Derivative; FMP-CCA
EINECS	Contact for details

Quality Control

Our trans-2-(3-Fluoro-4-Methoxyphenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.