Description

Sodium 2,3-Difluorobenzoate is the sodium salt derivative of 2,3-difluorobenzoic acid, a valuable fluorinated aromatic building block. This compound is a key intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and lipophilicity. It is primarily required by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-cancer agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro-substituted aromatic ring enhances product efficacy and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and electronic materials to alter thermal and electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated motifs.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new synthetic methodologies involving fluorinated arenes.

Basic Information

Item	Details
Product Name	Sodium 2,3-Difluorobenzoate
CAS No.	1604819-08-0
Molecular Formula	C7H3F2NaO2
Molecular Weight	180.08 g/mol
Synonyms	2,3-Difluorobenzoic Acid Sodium Salt; Benzoic acid, 2,3-difluoro-, sodium salt (1:1); Sodium 2,3-difluorobenzoate; 2,3-Difluorobenzoate sodium; 2,3-DFBA sodium salt
EINECS	Contact for details

Quality Control

Our Sodium 2,3-Difluorobenzoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.