Description

Benzoic Acid, 5-(Hydroxymethyl)-2-(Trifluoromethyl)-, Methyl Ester is a high-value, multifunctional fluorinated aromatic building block. This compound is engineered to provide a unique trifluoromethyl group and a hydroxymethyl ester moiety, offering significant advantages in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and device efficiency.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and stability.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex fluorinated aromatic structures in medicinal and materials chemistry.

Basic Information

Product Name	Benzoic Acid, 5-(Hydroxymethyl)-2-(Trifluoromethyl)-, Methyl Ester
CAS No.	1567667-05-3
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	Methyl 5-(hydroxymethyl)-2-(trifluoromethyl)benzoate; 2-(Trifluoromethyl)-5-(hydroxymethyl)benzoic Acid Methyl Ester; 5-(Hydroxymethyl)-2-(trifluoromethyl)benzoic Acid Methyl Ester; Benzoic acid, 5-(hydroxymethyl)-2-(trifluoromethyl)-, methyl ester; Methyl 2-trifluoromethyl-5-hydroxymethylbenzoate
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 5-(Hydroxymethyl)-2-(Trifluoromethyl)-, Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is hygroscopic (moisture-sensitive); ensure containers are sealed after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.