Description

Benzamide, n-Ethyl-5-Fluoro-2-Hydroxy-n-(1-Methylethyl)- is a specialized fluorinated benzamide derivative, a high-value intermediate in modern synthetic chemistry. This compound matters for its role as a critical building block in the development of advanced pharmaceutical agents and agrochemicals, where its unique substitution pattern enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a fluorinated hydroxybenzamide scaffold into novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental stability.
• Chemical Research & Development: Acts as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value molecules for specialty applications.
• Ligand and Catalyst Development: Potential use in creating novel ligands for catalytic systems or as a component in material science.

Basic Information

Product Name	Benzamide, n-Ethyl-5-Fluoro-2-Hydroxy-n-(1-Methylethyl)-
CAS No.	1549490-65-4
Molecular Formula	C12H16FNO2
Molecular Weight	225.26 g/mol
Synonyms	N-Ethyl-5-fluoro-2-hydroxy-N-isopropylbenzamide; 5-Fluoro-2-hydroxy-N-ethyl-N-isopropylbenzamide; 2-Hydroxy-5-fluoro-N-ethyl-N-(1-methylethyl)benzamide; N-Ethyl-N-isopropyl-5-fluoro-2-hydroxybenzamide; Benzamide, 5-fluoro-2-hydroxy-N-ethyl-N-(1-methylethyl)-; 1549490-65-4; Fluorinated hydroxybenzamide derivative
EINECS	Contact for details

Quality Control

Our production of Benzamide, n-Ethyl-5-Fluoro-2-Hydroxy-n-(1-Methylethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support development and commercial projects with quality standards suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.