Description

3-Amino-5-Chloro-4-Fluoro-Benzoic Acid is a high-purity, multi-functional benzoic acid derivative distinguished by its unique halogen and amino substitution pattern. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel active ingredients. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific structural motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents due to its reactive amino and carboxylic acid groups.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific halogenated aniline-benzoic acid architectures.

Basic Information

Product Name	3-Amino-5-Chloro-4-Fluoro-Benzoic Acid
CAS No.	1547854-99-8
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	5-Chloro-4-fluoro-3-aminobenzoic acid; 3-Amino-5-chloro-4-fluorobenzoic acid; Benzoic acid, 3-amino-5-chloro-4-fluoro-; 4-Fluoro-3-amino-5-chlorobenzoic acid; 1547854-99-8; 3-Amino-4-fluoro-5-chlorobenzoic acid; 5-Chloro-4-fluoro-anthranilic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Chloro-4-Fluoro-Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.