Description

2-(5-Fluoro-2,3-dihydro-1-benzofuran-2-yl)acetic acid is a high-purity fluorinated benzofuran derivative serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique fused-ring structure with a fluorine substituent and acetic acid side chain makes it a valuable building block for constructing complex molecules with targeted biological activity. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated benzofuran scaffold.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides or fungicides with enhanced activity and selectivity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and chemical R&D projects.

Basic Information

Product Name	2-(5-Fluoro-2,3-dihydro-1-benzofuran-2-yl)acetic Acid
CAS No.	1529280-40-7
Molecular Formula	C₁₀H₉FO₃
Molecular Weight	196.18 g/mol
Synonyms	2-(5-Fluoro-2,3-dihydrobenzofuran-2-yl)acetic acid; 5-Fluoro-2,3-dihydro-1-benzofuran-2-acetic acid; 2-(5-Fluoro-2,3-dihydrobenzo[b]furan-2-yl)acetic acid; 1529280-40-7; 5-Fluoro-2,3-dihydrobenzofuran-2-ylacetic acid; Acetic acid, 2-(5-fluoro-2,3-dihydro-1-benzofuran-2-yl)-; 2-(5-Fluoro-2,3-dihydrobenzofuranyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(5-Fluoro-2,3-dihydro-1-benzofuran-2-yl)acetic acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.