Description

4-Bromo-2-Fluoro-5-Iodobenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization to introduce halogen atoms for modulating lipophilicity, bioavailability, and receptor binding affinity.
• Chemical Biology: Utilized as a probe or labeling reagent due to the presence of iodine, which can be used for radio-labeling or as a heavy atom in crystallography.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	4-Bromo-2-Fluoro-5-Iodobenzoic Acid
CAS No.	1521585-65-8
Molecular Formula	C7H3BrFIO2
Molecular Weight	354.90 g/mol
Synonyms	5-Iodo-4-bromo-2-fluorobenzoic acid; 2-Fluoro-4-bromo-5-iodobenzoic acid; Benzoic acid, 4-bromo-2-fluoro-5-iodo-; 4-Bromo-2-fluoro-5-iodobenzoic acid; 1521585-65-8; 4-Br-2-F-5-I-BA
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.