Description

Ethyl 5-Bromo-2-Fluoro-3-Methylbenzoate is a high-purity fluorinated and brominated aromatic ester, serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical spaces in medicinal chemistry.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Ethyl 5-Bromo-2-Fluoro-3-Methylbenzoate
CAS No.	1515410-82-8
Molecular Formula	C10H10BrFO2
Molecular Weight	261.09 g/mol
Synonyms	5-Bromo-2-fluoro-3-methylbenzoic acid ethyl ester; Ethyl 5-bromo-2-fluoro-m-toluate; Benzoic acid, 5-bromo-2-fluoro-3-methyl-, ethyl ester; 3-Methyl-5-bromo-2-fluorobenzoic acid ethyl ester; 1515410-82-8; Ethyl 5-bromo-2-fluoro-3-methylbenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-Fluoro-3-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.