Description

Methyl 6-Bromo-3-Chloro-2-Fluorobenzoate is a high-purity, multi-halogenated benzoate ester serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where its specific halogen substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and halogen atoms for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals, where the benzoate core and halogens influence material properties.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent in probe development for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, halogenated target molecules for clients.

Basic Information

Product Name	Methyl 6-Bromo-3-Chloro-2-Fluorobenzoate
CAS No.	1505850-20-3
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	Methyl 2-Fluoro-3-chloro-6-bromobenzoate; 6-Bromo-3-chloro-2-fluorobenzoic Acid Methyl Ester; Benzoic acid, 6-bromo-3-chloro-2-fluoro-, methyl ester; Methyl 6-bromo-3-chloro-2-fluorobenzoate; 2-Fluoro-3-chloro-6-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Bromo-3-Chloro-2-Fluorobenzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.