Description

Ethyl 3-Bromo-2,5-difluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the 3-bromo-2,5-difluorobenzoate moiety into complex molecular architectures, enabling precise structural modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromine and fluorine substituents are critical for biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, molecular probes, and other tools for biochemical research.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Ethyl 3-Bromo-2,5-difluorobenzoate
CAS No.	1504876-00-9
Molecular Formula	C9H7BrF2O2
Molecular Weight	265.05 g/mol
Synonyms	3-Bromo-2,5-difluorobenzoic Acid Ethyl Ester; Ethyl 3-Bromo-2,5-difluorobenzoate; Benzoic acid, 3-bromo-2,5-difluoro-, ethyl ester; 2,5-Difluoro-3-bromobenzoic Acid Ethyl Ester; Ethyl 3-Bromo-2,5-difluorobenzoate (CAS 1504876-00-9)
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-2,5-difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.