Description

Piribedil Dihydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial and research interest. Its primary value lies in its role as a precursor for the synthesis of Piribedil, a dopamine agonist used in neurological research and therapeutic applications. This compound is essential for manufacturers and research institutions in the pharmaceutical and life science sectors requiring reliable, high-quality building blocks for drug development and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of the active pharmaceutical ingredient Piribedil.
• Neurological Research: Used in preclinical and clinical studies investigating dopamine receptor activity and related pathways.
• API Manufacturing: Serves as a critical raw material in the commercial production of finished dosage forms.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies exploring Parkinson's disease and other movement disorders.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Piribedil Dihydrochloride
CAS No.	1451048-94-4
Molecular Formula	C16H24N2O2 • 2HCl
Molecular Weight	357.30 g/mol
Synonyms	Piribedil HCl; Piribedil Hydrochloride; 1-(3,4-Methylenedioxybenzyl)-4-(2-pyrimidinyl)piperazine Dihydrochloride; Trivastal Impurity; Piribedil Dihydrochloride Salt; 2-Pyrimidinylpiperazine Derivative Dihydrochloride; Piribedil Dihydrochloride (API)
EINECS	Contact for details

Quality Control

Our Piribedil Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.