Description

4-Fluoro-3-((4-Hydroxypiperidin-1-Yl)Sulfonyl)-n-(3,4,5-Trifluorophenyl)Benzamide is a sophisticated, high-purity organic intermediate designed for advanced chemical synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical research and development organizations need this precise chemical to enable the synthesis of next-generation drug candidates, leveraging its unique trifluorophenyl and sulfonyl-piperidine motifs.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for small molecule drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Protease Inhibitor Development: The sulfonamide and benzamide functional groups make it a candidate scaffold for designing enzyme inhibitors.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled compounds or probes used in biochemical and cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex target molecules under cGMP conditions.

Basic Information

Product Name	4-Fluoro-3-((4-Hydroxypiperidin-1-Yl)Sulfonyl)-n-(3,4,5-Trifluorophenyl)Benzamide
CAS No.	1445790-55-5
Molecular Formula	C18H15F4N2O4S
Molecular Weight	431.38 g/mol
Synonyms	N-(3,4,5-Trifluorophenyl)-4-fluoro-3-[(4-hydroxypiperidin-1-yl)sulfonyl]benzamide; 4-Fluoro-3-[(4-hydroxypiperidin-1-yl)sulfonyl]-N-(3,4,5-trifluorophenyl)benzamide; Benzamide, 4-fluoro-3-((4-hydroxy-1-piperidinyl)sulfonyl)-N-(3,4,5-trifluorophenyl)-; 1445790-55-5; 4-Fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-((4-Hydroxypiperidin-1-Yl)Sulfonyl)-n-(3,4,5-Trifluorophenyl)Benzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 standards, and material can be supplied to meet the stringent requirements of cGMP for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.