Description

4-Chloro-2-Fluoro-5-Iodo-Benzoic Acid is a high-purity, multi-halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by pharmaceutical R&D teams and agrochemical manufacturers for the development of new active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the halogen pattern can influence bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for synthesizing organic semiconductors, liquid crystals, and other functional materials requiring precise halogen substitution.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity halogenated aromatics.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in related chemical processes.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Iodo-Benzoic Acid
CAS No.	1440526-33-9
Molecular Formula	C7H3ClFIO2
Molecular Weight	315.45 g/mol
Synonyms	5-Iodo-4-chloro-2-fluorobenzoic acid; 4-Chloro-2-fluoro-5-iodobenzoic acid; Benzoic acid, 4-chloro-2-fluoro-5-iodo-; 2-Fluoro-4-chloro-5-iodobenzoic acid; 4-Chloro-2-fluoro-5-iodo-benzoic acid (IUPAC); 5-Iodo-4-chloro-2-fluoro-benzoic acid; CAS 1440526-33-9
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Fluoro-5-Iodo-Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and ensure compliance with relevant industry guidelines for advanced intermediates. A detailed Certificate of Analysis (COA), including results for purity, identity, and impurity profiles, is supplied with each shipment to guarantee consistent quality and batch-to-batch reproducibility for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.