Description

1-[(3-Fluorophenyl)Methyl]Cyclobutane-1-Carboxylic Acid is a high-purity fluorinated cyclobutane carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique structural combination of a cyclobutane ring and a fluorinated benzyl group, enabling precise molecular modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and fine-tuning the physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom and rigid cyclobutane core can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing sophisticated chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers or polymers with tailored properties for high-performance materials.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated, sterically constrained carboxylic acid derivatives.

Basic Information

Product Name	1-[(3-Fluorophenyl)Methyl]Cyclobutane-1-Carboxylic Acid
CAS No.	1439903-06-6
Molecular Formula	C12H13FO2
Molecular Weight	208.23 g/mol
Synonyms	1-[(3-Fluorobenzyl)]cyclobutane-1-carboxylic acid; 3-Fluorobenzylcyclobutane-1-carboxylic Acid; (3-Fluorobenzyl)cyclobutanecarboxylic Acid; 1-(3-Fluorobenzyl)cyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 1-[(3-fluorophenyl)methyl]-; 1439903-06-6; 1-(3-Fluorobenzyl)-1-cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 1-[(3-Fluorophenyl)Methyl]Cyclobutane-1-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.