Description

1-[3-(Trifluoromethyl)Phenyl]Methylcyclobutane-1-Carboxylic Acid is a high-value fluorinated organic building block characterized by its unique cyclobutane core and trifluoromethylphenyl moiety. This compound is critical for medicinal chemistry and advanced materials research, where its structure enables the fine-tuning of physicochemical properties like lipophilicity and metabolic stability. It is primarily sought after by pharmaceutical R&D teams and specialty chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced, high-performance pesticides and herbicides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance or low surface energy to advanced polymers.
• Chemical Research & Development: Employed as a versatile scaffold in academic and industrial labs for exploring new chemical spaces and reaction pathways.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethylphenyl group into complex molecular architectures.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Methylcyclobutane-1-Carboxylic Acid
CAS No.	1439902-85-8
Molecular Formula	C13H13F3O2
Molecular Weight	258.24 g/mol
Synonyms	1-[(3-Trifluoromethyl)phenyl]methylcyclobutane-1-carboxylic acid; 1-[(3-Trifluoromethyl)benzyl]cyclobutane-1-carboxylic acid; 1-((3-(Trifluoromethyl)phenyl)methyl)cyclobutane-1-carboxylic acid; α-(3-Trifluoromethylbenzyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-[(3-(trifluoromethyl)phenyl)methyl]-; 1-(3-Trifluoromethyl-benzyl)-cyclobutane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-[3-(Trifluoromethyl)Phenyl]Methylcyclobutane-1-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications. We operate under a cGMP-compliant quality system suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.