Description

4-Fluoro-2-Methyl-Benzoic Acid tert-Butyl Ester is a high-purity fluorinated benzoic acid derivative, serving as a critical protected intermediate in advanced organic synthesis. Its value lies in the strategic combination of the fluorine substituent and the acid-labile tert-butyl ester protecting group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Reagent: A versatile intermediate for introducing the 4-fluoro-2-methyl-benzoate moiety into more complex molecular architectures via coupling or deprotection reactions.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways involving fluorinated aromatics.

Basic Information

Item	Details
Product Name	4-Fluoro-2-Methyl-Benzoic Acid tert-Butyl Ester
CAS No.	1438382-28-5
Molecular Formula	C12H15FO2
Molecular Weight	210.25 g/mol
Synonyms	tert-Butyl 4-Fluoro-2-methylbenzoate; 4-Fluoro-2-methylbenzoic acid tert-butyl ester; 2-Methyl-4-fluorobenzoic acid tert-butyl ester; Benzoic acid, 4-fluoro-2-methyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-fluoro-2-methylbenzoate; 4-Fluoro-o-toluic acid tert-butyl ester; tert-Butyl 4-fluoro-o-toluate
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methyl-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.