Description

2,2-Difluoro-2-Mesitylacetic Acid is a specialized fluorinated organic acid building block. This compound is valued for its unique mesityl and difluoroacetic acid structure, which imparts specific steric and electronic properties critical for advanced synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the difluoroacetic acid group can influence biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and specialty materials where fluorine incorporation modifies surface properties and stability.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of biomolecules for mechanistic studies and diagnostic applications.

Basic Information

Product Name	2,2-Difluoro-2-Mesitylacetic Acid
CAS No.	1436389-32-0
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	2-Mesityl-2,2-difluoroacetic Acid; α,α-Difluoro-2,4,6-trimethylphenylacetic Acid; 2,2-Difluoro-2-(2,4,6-trimethylphenyl)acetic Acid; Mesityldifluoroacetic Acid; DFMAA; 2-(2,4,6-Trimethylphenyl)-2,2-difluoroethanoic Acid
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-Mesitylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.