Description

2-Amino-3-Bromo-5-Trifluoromethyl-Benzoic Acid is a high-value, multi-functional aromatic building block designed for advanced chemical synthesis. Its molecular structure, featuring amino, bromo, and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker for creating chemical probes and affinity tags to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Amino-3-Bromo-5-Trifluoromethyl-Benzoic Acid
CAS No.	1434631-44-3
Molecular Formula	C8H5BrF3NO2
Molecular Weight	284.03 g/mol
Synonyms	3-Bromo-2-amino-5-(trifluoromethyl)benzoic acid; 2-Amino-3-bromo-α,α,α-trifluoro-p-toluic acid; Benzoic acid, 2-amino-3-bromo-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-amino-3-bromobenzoic acid; 3-Bromo-2-amino-α,α,α-trifluoro-p-toluic acid; 2-Amino-3-bromo-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Bromo-5-Trifluoromethyl-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.