Description

(S)-Fesoterodine Fumarate CAS NO 1431511-18-0 is the single enantiomer of the active pharmaceutical ingredient fesoterodine fumarate, representing a high-purity chiral intermediate of significant therapeutic value. This compound is critical for the research and development of enantiomerically pure antimuscarinic agents, offering superior specificity and reduced side-effect profiles compared to racemic mixtures. It is primarily required by pharmaceutical R&D laboratories, process chemists, and manufacturers engaged in the synthesis of advanced urological medications and novel chiral drug candidates.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of (S)-Fesoterodine, the active enantiomer of the antimuscarinic drug.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing enantiopure formulations targeting overactive bladder (OAB) syndrome.
• Process Chemistry & Scale-Up: Serves as a critical starting material or intermediate in process optimization and pilot-scale manufacturing of chiral pharmaceuticals.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical analysis.
• Chiral Catalyst & Ligand Studies: Investigated in asymmetric synthesis research for the development of novel catalytic systems.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway studies related to fesoterodine and its derivatives.

Basic Information

Product Name	(S)-Fesoterodine Fumarate
CAS No.	1431511-18-0
Molecular Formula	C32H40N2O10
Molecular Weight	612.67 g/mol
Synonyms	(2R)-2-[(1S)-3,4-Dihydro-1H-isoquinolin-2-yl]-1-phenylethyl (2S)-2-amino-3-methylbutanoate fumarate; (S)-Fesoterodine hydrogen fumarate; (S)-Fesoterodine Fumarate Salt; (S)-Fesoterodine Hemifumarate; Fesoterodine (S)-enantiomer fumarate; (S)-Feso; (S)-Fesoterodine
EINECS	Contact for details

Quality Control

Our (S)-Fesoterodine Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical R&D use. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.