Description

3-Chloro-2-Fluoro-4-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block distinguished by its unique halogen and trifluoromethyl substitution pattern. This compound is critically important for introducing specific steric, electronic, and lipophilic properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen functionalities.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and labeled compounds for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for fine chemical manufacturers offering bespoke synthesis services for client-specific molecules.

Basic Information

Product Name	3-Chloro-2-Fluoro-4-(Trifluoromethyl)Benzoic Acid
CAS No.	1431329-63-3
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	3-Chloro-2-fluoro-4-(trifluoromethyl)benzoic acid; 2-Fluoro-3-chloro-α,α,α-trifluoro-p-toluic acid; Benzoic acid, 3-chloro-2-fluoro-4-(trifluoromethyl)-; 1431329-63-3; 3-Chloro-2-fluoro-4-trifluoromethylbenzoic acid; 4-(Trifluoromethyl)-3-chloro-2-fluorobenzoic acid
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and MS, to verify identity and purity against stringent internal specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.