Description

2,5-Difluoro-4-Morpholin-4-Ylbenzoic Acid is a high-purity, multifunctional aromatic building block featuring both a carboxylic acid and a morpholine moiety. This compound is critically important for medicinal chemistry and advanced materials research, serving as a versatile intermediate in the synthesis of complex molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its difluoro-substituted aromatic structure.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its rigid, substituted benzoic acid core.
• Chemical Synthesis: Utilized as a versatile synthon in organic chemistry for constructing complex molecular architectures via amide coupling or further functionalization.
• Bioconjugation & Probe Development: The carboxylic acid group enables conjugation to biomolecules for creating diagnostic probes or biochemical tools.

Basic Information

Product Name	2,5-Difluoro-4-Morpholin-4-Ylbenzoic Acid
CAS No.	1430223-92-9
Molecular Formula	C11H11F2NO3
Molecular Weight	243.21 g/mol
Synonyms	4-(2,5-Difluorophenyl)morpholine-4-carboxylic acid; 2,5-Difluoro-4-morpholinobenzoic acid; Benzoic acid, 2,5-difluoro-4-morpholino-; 4-Morpholino-2,5-difluorobenzoic acid; 2,5-Difluoro-4-(morpholin-4-yl)benzoic acid; 1430223-92-9; 2,5-Difluoro-4-morpholin-4-yl-benzoic acid
EINECS	Contact for details

Quality Control

Our production of 2,5-Difluoro-4-Morpholin-4-Ylbenzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.