Description

2-Chloro-5-Fluoro-3-Methylbenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen and methyl substituents, which enable precise structural modifications for developing novel compounds. This intermediate is essential for research and production teams in the pharmaceutical and agrochemical sectors, particularly for creating active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the chloro-fluoro-methyl substitution pattern enhances biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A versatile building block for custom chemical synthesis and scale-up projects in fine chemical production.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical entities.

Basic Information

Product Name	2-Chloro-5-Fluoro-3-Methylbenzoic Acid
CAS No.	1427416-28-1
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	2-Chloro-5-fluoro-3-methylbenzoic acid; 3-Methyl-2-chloro-5-fluorobenzoic acid; Benzoic acid, 2-chloro-5-fluoro-3-methyl-; 2-Chloro-5-fluoro-m-toluic acid; 5-Fluoro-2-chloro-3-methylbenzoic acid; 2-Chloro-5-fluoro-3-methyl-benzoic acid; 1427416-28-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-3-Methylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.