Description

3-Bromo-2-Fluoro-4-Methyl-Benzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery for oncology and central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and brominated organic compounds used in electronic displays.
• Organic Synthesis Building Block: Enables the introduction of bromo and fluoro substituents via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for complex molecule construction.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Coordination Chemistry Ligand: Potential precursor for designing novel ligands in catalytic and metal-organic framework (MOF) applications.

Basic Information

Item	Detail
Product Name	3-Bromo-2-Fluoro-4-Methyl-Benzoic Acid
CAS No.	1427382-06-6
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	3-Bromo-2-fluoro-p-toluic acid; 2-Fluoro-3-bromo-4-methylbenzoic acid; 4-Methyl-3-bromo-2-fluorobenzoic acid; Benzoic acid, 3-bromo-2-fluoro-4-methyl-; 1427382-06-6; 3-Br-2-F-4-Me-BA
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-4-Methyl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.