Description

2-Fluoro-5-Iodo-4-Methyl-Benzoic Acid Methyl Ester is a high-value, multi-functional aromatic building block designed for advanced organic synthesis. This compound matters for its unique halogenated structure, which provides distinct reactivity for constructing complex molecules with tailored electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as drug discovery, ligand synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide candidates, leveraging the fluorine and iodine substituents for bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and photoactive compounds due to its halogenated aromatic core.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs serving the global fine chemical market.
• Academic & Institutional Research: Used in university and institutional labs for fundamental studies in organic synthesis and reaction methodology development.

Basic Information

Product Name	2-Fluoro-5-Iodo-4-Methyl-Benzoic Acid Methyl Ester
CAS No.	1427195-21-8
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Methyl 2-Fluoro-5-Iodo-4-Methylbenzoate; 4-Methyl-2-fluoro-5-iodobenzoic Acid Methyl Ester; Benzoic acid, 2-fluoro-5-iodo-4-methyl-, methyl ester; 2-Fluoro-4-methyl-5-iodobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodo-4-Methyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.