Description

4-Acetyl-3-Fluorobenzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the strategic placement of fluorine and acetyl groups enables precise modulation of biological activity and physicochemical properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and material science programs.

Application

• Critical intermediate in the synthesis of pharmaceutical candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Building block for advanced agrochemicals, including herbicides and fungicides, where fluorination enhances stability and efficacy.
• Precursor in material science for creating functionalized polymers and liquid crystal compounds.
• Key reagent in academic and industrial research for exploring structure-activity relationships (SAR) in medicinal chemistry.
• Used in the development of diagnostic agents and imaging probes.
• Intermediate for synthesizing more complex fluorinated benzoic acid derivatives.

Basic Information

Product Name	4-Acetyl-3-Fluorobenzoic Acid
CAS No.	1427082-83-4
Molecular Formula	C9H7FO3
Molecular Weight	182.15 g/mol
Synonyms	3-Fluoro-4-acetylbenzoic acid; 4-Acetyl-3-fluorobenzoic acid; Benzoic acid, 4-acetyl-3-fluoro-; 3-Fluoro-4-acetylbenzoic acid; 4-Acetyl-3-fluoro-benzoic acid; 4-Acetyl-m-fluorobenzoic acid; 3-Fluoro-4-acetyl-benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Acetyl-3-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.