Description

Benzoic Acid, 3-Fluoro-4-[(Methylamino)Carbonyl]- is a high-value, fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a methylamide group, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine moiety enhances bioactivity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in diagnostic and bio-imaging applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	Benzoic Acid, 3-Fluoro-4-[(Methylamino)Carbonyl]-
CAS No.	1427081-81-9
Molecular Formula	C9H8FNO3
Molecular Weight	197.16 g/mol
Synonyms	3-Fluoro-4-[(methylcarbamoyl)]benzoic acid; 4-Carboxy-2-fluoro-N-methylbenzamide; 2-Fluoro-4-(N-methylcarbamoyl)benzoic acid; N-Methyl-2-fluoro-4-carbamoylbenzoic acid; 3-Fluoro-4-(N-methylaminocarbonyl)benzoic acid; 1427081-81-9; Benzoic acid, 3-fluoro-4-[(methylamino)carbonyl]- (9CI)
EINECS	Contact for details

Quality Control

Every batch of Benzoic Acid, 3-Fluoro-4-[(Methylamino)Carbonyl]- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles. Our quality protocols are designed to support regulatory filings, including those for IND/NDA applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.