Description

5-Fluoro-1H-Benzo[D][1,2,3]Triazole-6-Carboxylic Acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its dual functionality, combining a reactive carboxylic acid group with a fluorinated benzotriazole core, enabling precise molecular modifications. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery programs, particularly for candidates targeting kinases and other enzymes.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as polymers or organic electronic components with tailored properties.
• Chemical Biology Probes: Useful for designing fluorescent tags or activity-based probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Fluoro-1H-Benzo[D][1,2,3]Triazole-6-Carboxylic Acid
CAS No.	1427081-62-6
Molecular Formula	C7H4FN3O2
Molecular Weight	181.13 g/mol
Synonyms	5-Fluoro-1H-benzotriazole-6-carboxylic acid; 5-Fluoro-1H-1,2,3-benzotriazole-6-carboxylic acid; 6-Carboxy-5-fluorobenzotriazole; 5-Fluoro-1H-benzo[d][1,2,3]triazole-6-carboxylic acid; 1427081-62-6; 5-F-BTZ-6-COOH; Fluorobenzotriazole carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Benzo[D][1,2,3]Triazole-6-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For cGMP or other specific regulatory requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.