Description

Gsk1521498 CAS NO 1426543-84-1 is a high-purity, small molecule compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly in the areas of oncology, metabolic disorders, and central nervous system (CNS) diseases.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Biochemical Research: Used as a reference standard or probe compound in high-throughput screening (HTS) and assay development.
• Preclinical Studies: Essential for pharmacokinetic (PK), pharmacodynamic (PD), and toxicology studies in animal models.
• API Development: Serves as the core structure for the development of Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for investigating disease mechanisms and identifying new therapeutic targets.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.

Basic Information

Product Name	Gsk1521498
CAS No.	1426543-84-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GSK1521498; GSK-1521498; UNII-9Q5Y2F0F5I; 1426543-84-1; (3S)-3-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]methyl]-1-(2,2,2-trifluoroethyl)-3,8-diazabicyclo[3.2.1]octane-2,4-dione; GSK1521498 free base
EINECS	Contact for details

Quality Control

Our Gsk1521498 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We can support development projects with materials suitable for research use, as well as supply under GMP guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.