Description

Sodium 3-Chloro-4-Fluorobenzoate is a high-purity, organofluorine building block salt essential for advanced chemical synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogen substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce benzoate motifs with chloro and fluoro functionalities.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies.
• Polymer Modification: Acts as a monomer or additive to introduce specific functional groups into polymer chains, altering material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution due to its reactive halogen sites.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial labs for exploring new fluorinated compound libraries.

Basic Information

Product Name	Sodium 3-Chloro-4-Fluorobenzoate
CAS No.	1421761-18-3
Molecular Formula	C7H3ClFNaO2
Molecular Weight	196.54 g/mol
Synonyms	Benzoic acid, 3-chloro-4-fluoro-, sodium salt (1:1); 3-Chloro-4-fluorobenzoic acid sodium salt; Sodium 3-chloro-4-fluorobenzoate; 4-Fluoro-3-chlorobenzoic acid sodium salt; 3-Chloro-4-fluorobenzoate sodium; Sodium (3-chloro-4-fluorophenyl)formate; Na-3-Cl-4-F-Bz; 1421761-18-3
EINECS	Contact for details

Quality Control

Our Sodium 3-Chloro-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.