Description

2-Chloro-4,5-Difluorobenzoic Acid Sodium Salt is a high-value, multi-functional aromatic building block essential for advanced chemical synthesis. Its core value lies in the strategic positioning of halogen and fluorine substituents on the benzoic acid core, which enables precise modulation of electronic properties, lipophilicity, and metabolic stability in target molecules. This compound is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in creating novel herbicides, fungicides, and active pharmaceutical intermediates (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents, where the difluoro and chloro groups enhance binding affinity and bioavailability.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of next-generation herbicides and fungicides, leveraging the halogenated benzoic acid structure for improved pest selectivity and environmental profile.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic materials, where its aromatic fluorinated structure contributes to the desired dielectric anisotropy and thermal stability.
• Organic Ligand Preparation: Acts as a starting material for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRAM) for producing tailored fluorinated compounds for various high-tech applications.

Basic Information

Product Name	2-Chloro-4,5-Difluorobenzoic Acid Sodium Salt
CAS No.	1421761-16-1
Molecular Formula	C7H2ClF2NaO2
Molecular Weight	214.53 g/mol
Synonyms	Sodium 2-Chloro-4,5-difluorobenzoate; Benzoic acid, 2-chloro-4,5-difluoro-, sodium salt (1:1); 2-Chloro-4,5-difluorobenzoic acid sodium; 4,5-Difluoro-2-chlorobenzoic acid sodium salt; 2-Chloro-4,5-difluorobenzoate sodium; Sodium 4,5-difluoro-2-chlorobenzoate; 1421761-16-1 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4,5-Difluorobenzoic Acid Sodium Salt is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with precise customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.