Description

2-Fluoro-5-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts desirable electronic and steric properties to target molecules, enhancing their metabolic stability and lipophilicity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring fine-tuned molecular interactions.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to introduce fluorine functionality into specialty polymers, enhancing chemical resistance and surface properties.
• Chemical Research & Development: A versatile reagent for exploring new reactions in fluoroorganic chemistry and synthesizing complex, fluorinated molecular architectures.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Cinnamic Acid
CAS No.	1413913-80-0
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	(E)-3-[2-Fluoro-5-(trifluoromethyl)phenyl]acrylic acid; 2-Fluoro-α,5-bis(trifluoromethyl)cinnamic acid; (2E)-3-[2-Fluoro-5-(trifluoromethyl)phenyl]prop-2-enoic acid; 2-Fluoro-5-trifluoromethylcinnamic acid; 2-Fluoro-5-(trifluoromethyl)benzeneacrylic acid; 1413913-80-0; FTFC Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Cinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.