Description

Tamsulosin CAS NO 1396967-49-9 is a high-purity active pharmaceutical ingredient (API) belonging to the class of selective α1-adrenergic receptor antagonists. This compound is of critical importance for its therapeutic efficacy in treating benign prostatic hyperplasia (BPH) by relaxing smooth muscle in the prostate and bladder neck. It is an essential raw material for global pharmaceutical manufacturers engaged in the production of prescription medications for urological conditions, requiring stringent quality control and reliable supply chains.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of Benign Prostatic Hyperplasia (BPH).
• Controlled-Release Formulations: Used in the development and production of extended-release capsules and tablets to ensure steady plasma concentration.
• Generic Drug Manufacturing: A key component for companies producing bioequivalent versions of branded α-blocker drugs.
• Clinical Research: Serves as a reference standard and raw material in preclinical and clinical studies for new urological therapies.
• Veterinary Medicine: Investigational use in treating urinary obstruction in animals, particularly in canine patients.
• Combination Therapies: Utilized in fixed-dose combination drugs alongside other agents like dutasteride for enhanced BPH management.

Basic Information

Product Name	Tamsulosin
CAS No.	1396967-49-9
Molecular Formula	C₂₀H₂₈N₂O₅S
Molecular Weight	408.51 g/mol
Synonyms	YM-12617; Tamsulosin Hydrochloride; Flomax (Brand Name); (R)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide; AMS; α1A-Adrenoceptor Antagonist
EINECS	Contact for details

Quality Control

Our Tamsulosin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmacopeial standards, including identification, assay, impurity profiling, and residual solvent analysis. Certificates of Analysis (COA) documenting compliance with relevant specifications (e.g., USP, EP, or in-house pharmacopeia) are provided with every shipment to guarantee traceability and quality assurance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Optical Rotation	-10.0° to -12.0° (c=1 in methanol)
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	NMT 1.0% w/w
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.