Description

Methyl 2-Fluoro-3-Hydroxy-5-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and nitro-substituted aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its fluorine atom for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Acts as a versatile building block for further derivatization, including ester hydrolysis, nitro group reduction, and nucleophilic aromatic substitution reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory chemistry projects.

Basic Information

Product Name	Methyl 2-Fluoro-3-Hydroxy-5-Nitrobenzoate
CAS No.	1394977-92-4
Molecular Formula	C8H6FNO5
Molecular Weight	215.14 g/mol
Synonyms	2-Fluoro-3-hydroxy-5-nitrobenzoic acid methyl ester; Methyl 2-fluoro-3-hydroxy-5-nitrobenzoate; Benzoic acid, 2-fluoro-3-hydroxy-5-nitro-, methyl ester; Methyl 5-nitro-2-fluoro-3-hydroxybenzoate; 3-Hydroxy-2-fluoro-5-nitrobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-3-Hydroxy-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.