Description

3-Fluoro-5-(2-Nitrophenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, where the fluorine atom can enhance bioavailability and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Functional Material Development: Employed in the research and production of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for biochemical and diagnostic research.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic methodology.

Basic Information

Item	Details
Product Name	3-Fluoro-5-(2-Nitrophenyl)Benzoic Acid
CAS No.	1393442-54-0
Molecular Formula	C13H8FNO4
Molecular Weight	261.21 g/mol
Synonyms	3-Fluoro-5-(2-nitrophenyl)benzoic acid; 2'-Nitro-3-fluoro-5-biphenylcarboxylic acid; 3-Fluoro-5-(o-nitrophenyl)benzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-2-nitro-; 3-Fluoro-5-(2-nitrophenyl)benzoic acid CAS 1393442-54-0; 3-Fluoro-5-(2-nitrophenyl)benzoic acid (CAS NO 1393442-54-0); 3-Fluoro-5-(2-nitrophenyl)benzoic acid, 1393442-54-0
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-(2-Nitrophenyl)Benzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes HPLC purity ≥98% (typical), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.