Description

4-Bromo-2,3,5,6-Tetrafluorobenzotrichloride is a highly functionalized halogenated aromatic building block of significant synthetic utility. Its unique structure, featuring bromine, fluorine, and trichloromethyl substituents, makes it a versatile precursor for advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors seeking to introduce complex fluorinated motifs into their target molecules. The CAS number for this compound is 1391033-28-5.

Application

This multi-functional intermediate is designed for advanced synthetic chemistry, enabling the construction of complex fluorinated structures.

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the metabolic stability and lipophilicity imparted by fluorine atoms.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorinated aromatic core enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated mesogens and electron-transport materials, crucial for high-performance display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: The bromine substituent provides a handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl systems.
• Nucleophilic Displacement: The trichloromethyl group can be hydrolyzed to a carboxylic acid or serve as a site for nucleophilic substitution, further diversifying its synthetic applications.

Basic Information

Product Name	4-Bromo-2,3,5,6-Tetrafluorobenzotrichloride
CAS No.	1391033-28-5
Molecular Formula	C7BrCl3F4
Molecular Weight	346.24 g/mol
Synonyms	1-Bromo-2,3,5,6-tetrafluoro-4-(trichloromethyl)benzene; Benzene, 1-bromo-2,3,5,6-tetrafluoro-4-(trichloromethyl)-; 4-Bromo-2,3,5,6-tetrafluoro-α,α,α-trichlorotoluene; 2,3,5,6-Tetrafluoro-4-bromobenzotrichloride; α,α,α-Trichloro-4-bromo-2,3,5,6-tetrafluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3,5,6-Tetrafluorobenzotrichloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. For long-term storage, keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.