Description

Dimethyl 2-Fluorobiphenyl-3,3'-Dicarboxylate is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which enables the construction of complex molecules for high-performance applications. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorinated biphenyl motifs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel fluorinated drug candidates targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the fluorine atom and biphenyl core enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials, contributing to improved performance in display and lighting technologies.
• Polymer & Specialty Chemicals: Acts as a monomer or modifier in the synthesis of high-performance polymers, coatings, and specialty chemicals requiring enhanced thermal and chemical resistance.
• Organic Synthesis & Catalysis Research: A versatile substrate in cross-coupling reactions (e.g., Suzuki, Stille) and as a ligand precursor in catalytic system development for academic and industrial research.

Basic Information

Product Name	Dimethyl 2-Fluorobiphenyl-3,3'-Dicarboxylate
CAS No.	1381944-85-9
Molecular Formula	C16H13FO4
Molecular Weight	288.27 g/mol
Synonyms	3,3'-Biphenyldicarboxylic acid, 2'-fluoro-, dimethyl ester; Dimethyl 2'-fluoro[1,1'-biphenyl]-3,3'-dicarboxylate; 2'-Fluorobiphenyl-3,3'-dicarboxylic acid dimethyl ester; 3,3'-(2-Fluorobiphenyl-4,4'-diyl)bis(propanoic acid) dimethyl ester (common misnomer); 2-Fluoro-3,3'-biphenyldicarboxylic Acid Dimethyl Ester; F-BPDM; [1,1'-Biphenyl]-3,3'-dicarboxylic acid, 2'-fluoro-, 1,1'-dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 2-Fluorobiphenyl-3,3'-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each lot, supporting your regulatory and quality assurance requirements for pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.