Description

4-[(3-Fluorophenyl)Methyl]Oxane-4-Carboxylic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. Its core value lies in its unique molecular scaffold, which combines a fluorinated aromatic moiety with a functionalized oxane ring, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential monomer or additive in the synthesis of specialty polymers with tailored thermal or optical properties.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated intermediates.

Basic Information

Product Name	4-[(3-Fluorophenyl)Methyl]Oxane-4-Carboxylic Acid
CAS No.	1380300-75-3
Molecular Formula	C13H15FO3
Molecular Weight	238.26 g/mol
Synonyms	4-[(3-Fluorobenzyl)]Tetrahydro-2H-pyran-4-carboxylic Acid; 4-(3-Fluorobenzyl)tetrahydro-2H-pyran-4-carboxylic Acid; 4-(3-Fluorobenzyl)oxane-4-carboxylic Acid; 3-Fluoro-α-(tetrahydro-2H-pyran-4-yl)benzenemethanol, 4-carboxy derivative; THP-4-Carboxylic Acid, 4-(3-Fluorobenzyl) Derivative; Fluorinated Oxane Carboxylic Acid Building Block
EINECS	Contact for details

Quality Control

Our 4-[(3-Fluorophenyl)Methyl]Oxane-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.