Description

3-(Bromomethyl)-5-Fluorobenzoicacid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a carboxylic acid function, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Useful for the preparation of fluorescent or affinity tags for studying biological processes.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	3-(Bromomethyl)-5-Fluorobenzoicacid
CAS No.	1379351-68-4
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	5-Fluoro-3-(bromomethyl)benzoic Acid; 3-Bromomethyl-5-fluorobenzoic Acid; Benzoic acid, 3-(bromomethyl)-5-fluoro-; 5-Fluoro-3-bromomethylbenzoic Acid; 3-(Bromomethyl)-5-fluorobenzoic Acid; 1379351-68-4; 5-Fluoro-3-(bromomethyl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(Bromomethyl)-5-Fluorobenzoicacid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profiles is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.