Description

Benzoic Acid, 3,4-Difluoro-5-Methyl-, Methyl Ester is a high-purity fluorinated aromatic ester building block, offering a unique combination of steric and electronic properties for advanced synthesis. This compound is valued for its role in modulating the physicochemical characteristics of target molecules, particularly in the development of active pharmaceutical ingredients and agrochemicals. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and methyl ester functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro and methyl ester groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing properties like chemical resistance, weatherability, and surface characteristics for high-performance coatings and resins.
• Organic Synthesis & Catalysis: A versatile reagent in academic and industrial R&D for constructing complex fluorinated aromatic systems and as a ligand precursor in catalytic systems.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing specialized fluorinated aromatic compounds used in high-value fragrance and flavor ingredients.

Basic Information

Product Name	Benzoic Acid, 3,4-Difluoro-5-Methyl-, Methyl Ester
CAS No.	1379218-01-5
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	Methyl 3,4-Difluoro-5-methylbenzoate; 3,4-Difluoro-5-methylbenzoic Acid Methyl Ester; 5-Methyl-3,4-difluorobenzoic Acid Methyl Ester; Benzoic Acid, 3,4-Difluoro-5-Methyl-, Methyl Ester; Methyl 5-Methyl-3,4-difluorobenzoate; 3,4-Difluoro-5-methyl Methyl Benzoate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and impurity profiles. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.