Description

4-Fluorobenzo[B]Thiophene-7-Carboxylic Acid CAS NO 1379164-23-4 is a high-value fluorinated heterocyclic building block, a benzo[b]thiophene derivative functionalized with both a fluorine atom and a carboxylic acid group. This unique structure makes it a critical intermediate for medicinal chemistry and advanced materials research, offering precise control over molecular properties. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated active ingredients for crop protection products, enhancing their efficacy and environmental profile.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors and light-emitting compounds, due to its fused thiophene core.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for its use in constructing complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) in fluorinated aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	4-Fluorobenzo[B]Thiophene-7-Carboxylic Acid
CAS No.	1379164-23-4
Molecular Formula	C9H5FO2S
Molecular Weight	196.20 g/mol
Synonyms	4-Fluorobenzo[b]thiophene-7-carboxylic acid; 7-Carboxy-4-fluorobenzo[b]thiophene; 4-Fluoro-1-benzothiophene-7-carboxylic acid; 4-Fluoro-benzo[b]thiophene-7-carboxylic acid; 4-F-BT-7-COOH; 4-F-7-CBA-BT; 1379164-23-4
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzo[B]Thiophene-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.