Description

3-Methyl-3-[4-(Trifluoromethyl)Phenyl]Butanoic Acid is a high-value, synthetically versatile organic compound featuring a trifluoromethylphenyl group. This structure makes it a critical building block for the development of advanced pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can dramatically alter a molecule's metabolic stability, lipophilicity, and bioactivity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for use in medicinal chemistry and as a key intermediate in custom synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening libraries and structure-activity relationship (SAR) studies to optimize lead compounds.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.
• Fluorine Chemistry Research: An important reagent for academic and industrial research focused on incorporating fluorine into complex organic molecules.

Basic Information

Product Name	3-Methyl-3-[4-(Trifluoromethyl)Phenyl]Butanoic Acid
CAS No.	1368768-62-0
Molecular Formula	C12H13F3O2
Molecular Weight	246.23 g/mol
Synonyms	3-Methyl-3-[4-(trifluoromethyl)phenyl]butyric acid; 3-Methyl-3-(4-trifluoromethylphenyl)butanoic acid; 4,4,4-Trifluoro-3-hydroxy-3-(4-trifluoromethylphenyl)butyric acid lactone (precursor); α,α-Dimethyl-4-(trifluoromethyl)benzenepropanoic acid; 3-Methyl-3-(p-trifluoromethylphenyl)butyric acid; Butanoic acid, 3-methyl-3-[4-(trifluoromethyl)phenyl]-; 1368768-62-0
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-3-[4-(Trifluoromethyl)Phenyl]Butanoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.